Clinical Evidence: Publications

Acne (Mild to Moderate Acne Vulgaris)Sadick NS. Handheld LED array device in the treatment of acne
vulgaris. Journal of Drugs in Dermatology. 2008; 7: 347-350Lee SY, You CE and Park MY. Blue and Red Light Combination LED
Phototherapy for Acne Vulgaris in Patients with Skin Phototype IV.
Lasers in Surgery and Medicine. 2007; 39: 180-188Tremblay JF, Sire DJ, Lowe NJ and Moy RL. Light-emitting diode 415
nm in the treatment of Inflammatory acne. Journal of Cosmetic and
Laser Therapy. 2006; 8: 31-33

Goldberg DJ and Russell BA. Combination blue (415 nm) and red
(633 nm) LED phototherapy in the treatment of mild to severe acne
vulgaris. Journal of Cosmetic and Laser Therapy. 2006; 8: 71-75

Morton CA, Scholefield RD, Whitehurst C and Birch J. An open study
to determine the efficacy of blue light in the treatment of mild to
moderate acne. Journal of Dermatological Treatment. 2005; 16:
219-223

Light Only Skin Rejuvenation (Periorbital Wrinkles)

Sadick NS. A study to determine the efficacy of a novel handheld
light-emitting diode device in the treatment of photoaged skin.
Journal of Cosmetic Dermatology. 2008; 7: 263-267

Baez F and Reilly LR. The use of light-emitting diode therapy in the
treatment of photoaged skin. Journal of Cosmetic Dermatology.
2007; 6: 189-194

Lee SY, et al. A prospective, randomized, placebo-controlled,
double-blinded, and split-face clinical study on LED phototherapy
for skin rejuvenation: Clinical, profilometric, histologic,
ultrastructural, and biochemical evaluations and comparison of
three different treatment settings. Journal of Photochemistry and
Photobiology B. 2007; 88: 51-67

Bhat J, Birch J, Whitehurst C and Lanigan SW. A Single-Blinded
Randomized Controlled Study to Determine the Efficacy of
Omnilux Revive Facial Treatment in Skin Rejuvenation. Lasers in
Medical Science. 2005; 20: 6-10

Russell BA, Kellett N and Reilly LR. A study to determine the efficacy
of combination LED light therapy (830 nm and 633 nm) in facial
skin rejuvenation. Journal of Cosmetic and Laser Therapy. 2005; 7:
196-200

Kim JW. Clinical trial of Non thermal 633nm Omnilux LED array
for renewal of Photoaging: Clinical Surface Profilometric Results.
Journal of the Korean society for Laser Medicine and Surgery. 2005;
9: 69-76

Pain Attenuation (Minor Muscle and Joint Pain)

Baxter GD, Bleakley C, Glasgow P and Calderhead RG. A near
infrared LED-based rehabilitation system: Initial clinical experience.
Laser Therapy. 2005; 14.1: 29-36

Trelles MA and Calderhead RG. Combined Infrared laser and LED
therapy for post mastectomy pain and discomfort: A case report.
Laser Therapy. 2005; 14.1: 41-45

Review and In-Vivo Studies (Basic Science)

Calderhead RG. The Photobiological Basics Behind Light-Emitting
Diode (LED) Phototherapy. Laser Therapy. 2007; 16.2: 97-108

Takezaki S, Omi T, Sato S and Kawana S. Light-emitting diode
phototherapy at 630 +/- 3 nm increases local levels of skin-honing
T-cells in human subjects. Journal of Nippon Medical School. 2006;
73: 75-81

Takezaki S, Omi T, Sato S and Kawana S. Ultrastructural
Observations Of Human Skin Following Irradiation With Visible Red
Light-Emitting Diodes (LEDs): A Preliminary In Vivo Report. Laser
Therapy. 2005; 14.4: 153-160

Calderhead RG. Laser resurfacing today – not all photoscience is photothermal. Journal of Cosmetic Dermatology. 2004; 2: 242-243